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A client is receiving a drug that is excreted in the bile. What will the best nursing assessment of the effect of this drug on the patient include?

  1. the effect of the drug will be decreased

  2. the effect of the drug will be decrease side effects

  3. the effect of the drug will be increase side effects

  4. the effect of the drug will be prolonged action

The correct answer is: the effect of the drug will be decreased

When a drug is excreted in the bile, it can be reabsorbed from the intestines back into the bloodstream through enterohepatic circulation. This means that more of the drug can stay in the body for a longer period, potentially leading to a prolonged action or increased effect of the drug. Therefore, the best nursing assessment in this case would include the understanding that the effect of the drug will be decreased, as less of the drug will be excreted out of the body, leading to a potential increase in its concentration and effects.